Association of sports activities in leisure time and incident myocardial infarction in middle-aged men and women from the general population: the MONICA/KORA Augsburg cohort study

  1. Christa Meisingera,b⇓
  2. Hannelore Löwelb
  3. Margit Heiera,b
  4. Ulla Kandlerb
  5. Angela Döringb
  1. aCentral Hospital of Augsburg, MONICA/KORA Myocardial Infarction Registry, Augsburg, Germany
  2. bGSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
  1. Correspondence to Christa Meisinger, MD, MPH Central Hospital of Augsburg, MONICA/KORA Myocardial Infarction Registry, Stenglinstr. 2 D-86156 Augsburg, Germany Tel: +49 821 400 4373; fax: +49 821 2838; e-mail: christa.meisinger@gsf.de

Abstract

Background To examine sex-specific associations between sports activities in leisure time and incident myocardial infarction (MI) in a representative population sample in Germany.

Design Cohort study.

Methods The study was based on 3501 men and 3475 women (aged 45-74 years) who participated in one of the three MONICA Augsburg surveys between 1984 and 1995 and were followed up until 2002. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated from Cox proportional hazard models.

Results A total of 295 cases of incident MIs among men and 91 among women were registered during a median follow-up period of 8.6 years. In both sexes, moderate and high level of sports activities in leisure time were associated with a reduced risk of incident MI after age and survey adjustment; the HRs of MIs associated with a moderate and high level of sports activities in leisure time were 0.68 (0.49-0.96), and 0.71 (0.50-0.99) for men and 0.42 (0.21-0.84), and 0.18 (0.04-0.74) for women. Further adjustment for other major coronary heart disease risk factors attenuated the HRs: in moderately and highly active men, the HRs were not significant anymore (HRs 0.78 and 0.84, respectively), but the HRs remained significantly reduced in moderately and highly active women (HR 0.49; 95% CI, 0.24-1.00 and HR 0.21; 95% CI, 0.05-0.87, respectively).

Conclusion Moderate or high levels of sports activities in leisure time are associated with a significantly reduced risk of MI in women, but not men from the general population. Eur J Cardiovasc Prev Rehabil 14: 788-792 © 2007 The European Society of Cardiology

 

  • Received December 17, 2006.
  • Accepted May 23, 2007.

 

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